ABC Transporter CslAB, a Stabilizer of ComCDE Signal in Streptococcus mutans
نویسندگان
چکیده
منابع مشابه
ABC Transporter CslAB, a Stabilizer of ComCDE Signal in Streptococcus mutans
BACKGROUND In Streptococcus mutans, ComCDE, a peptide-induced two-component signal transduction system, forms a closed signal transduction, and even if difunctional ComE closes this signal at its headstream to avoid its infinite amplification, it is not enough for ComE to work in a concentration-dependent manner. CslAB has a chance to regulate ComCDE by controlling extracellular competence-stim...
متن کاملabc transporter cslab, a stabilizer of comcde signal in streptococcus mutans
results pcslab is a weak promoter responding to come and its binding appears to be negative cooperative. although pcslab is partially controlled by comcde, it can respond to comcde regulation. supported by the obtained molecular evidence, cslab acts as a stabilizer of comcde signal on the patterns of its expression. conclusions pcslab is partially controlled by comcde. cslab is a stabilizer of ...
متن کاملRole of VltAB, an ABC transporter complex, in viologen tolerance in Streptococcus mutans.
Streptococcus mutans, a Gram-positive organism, is the primary causative agent in the formation of dental caries in humans. To persist in the oral cavity, S. mutans must be able to tolerate rapid environmental fluctuations and exposure to various toxic chemicals. However, the mechanisms underlying the ability of this cariogenic pathogen to survive and proliferate under harsh environmental condi...
متن کاملRole of ABC transporter proteins in stress responses of Streptococcus mutans.
Streptococcus mutans possesses a number of ATP-binding cassette (ABC) transporters, which function as multiple sugar metabolism transporters and are promising targets for antimicrobial strategies. In the present study, we performed functional analyses of SMu0836 and SMu0837 products, which are possible ABC transporters. Isogenic mutant strains Δ0836 and Δ0837 were generated by insertional inact...
متن کاملCharacterization of pit, a Streptococcus pneumoniae iron uptake ABC transporter.
Bacteria frequently have multiple mechanisms for acquiring iron, an essential micronutrient, from the environment. We have identified a four-gene Streptococcus pneumoniae operon, named pit, encoding proteins with similarity to components of a putative Brachyspira hyodysenteriae iron uptake ABC transporter, Bit. An S. pneumoniae strain containing a defined mutation in pit has impaired growth in ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Jundishapur Journal of Microbiology
سال: 2015
ISSN: 2008-3645,2008-4161
DOI: 10.5812/jjm.22965v2